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of Klebsiella, a clinically important pathogen. Combining eco-evolutionary theory, lab experiments, and genomic sequencing, you will help build and validate a model predicting how antibiotic selection shifts with
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models and combine them with cutting-edge technologies including CRISPR/Cas9 genome engineering, immunopeptidomics, single-cell multiomics, and functional immunology. The project is embedded in a
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disease (VWM) and metachromatic leukodystrophy (MLD). You will investigate the efficacy and safety of AAV gene therapy in VWM and MLD mouse models. In addition, you will use genome-editing approaches
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the Koch/Walden group at the Centre for Organismal Studies (COS), Heidelberg, the project explores how genome evolution drives the diversification of plant immune receptors and their capacity to recognize
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-groups/wang-group/ In the Wang Group, we develop and apply interdisciplinary technologies that bridge high-resolution spatial biology and genome-wide discovery. By integrating multi-omic sequencing and
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tumorigenesis. Genomic and single-cell approaches may also be used, supported by collaboration with computational scientists. References/further reading Zhu H, Chan ASL & Narita M. The rise of RAS: how gradual
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islet physiology and single-cell genomics to join the lab of Dr. Joan Camuñas. The lab of Dr. Joan Camuñas stands at the interface of genomics, biophysics and precision medicine. Our mission is to develop
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University of Texas Health Science Center San Antonio | San Antonio, Texas | United States | 43 minutes ago
Framingham Heart Study, CHARGE, International Genomics of Alzheimer’s Project, Alzheimer’s Disease Sequencing Project, International Stroke Genetics Consortium, and other major initiatives in which Biggs
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on developing probabilistic latent-variable methods for large and structured biological data, with applications in genomics, spatial transcriptomics, and fluorescence imaging. High-dimensional and structured
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on single-cell and spatial genomics data, from sequencing and imaging, and apply them to human developmental and disease biology. Possible research directions include: ● Generative models of cell–cell