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characterization of neofunctionalized enzymes in plant metabolism, 2) elucidation and engineering of biosynthetic pathways for high-value molecules from plants, and 3) identifying the native targets of bioactive
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transcription machinery, and mRNA processing enzymes and their interactions with RNApII. We welcome applications from recent PhD graduates who are interested in these or related fields, particularly those who may
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to join the Jamali Lab at the GBI. At the Jamali Lab, we are interested in developing new computational methods for the design of conformationally dynamic and functional enzymes. We will accomplish this by
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efforts in the group are: 1) generating large and diverse antibody sequence-affinity datasets to train affinity-aware antibody design models, 2) generating diverse sequence-function maps for enzymes
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, the characterization of biomaterials, or enzyme kinetics would be beneficial but is not required. Candidates should be excited to work at the interface of biology and chemistry and motivated to develop and apply
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) advance fundamental scientific understanding of molecular and cellular evolution, ii) develop biomolecules to tackle challenges in human-health and industry, and iii) generate large-scale enzyme datasets
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cells shape the collective function of bacterial pathogen cell populations during colonization and infection, ii) how previously undercharacterized hydrolytic enzymes and dynamic changes in chemical
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– protein interactions or enzyme optimization. Main responsibilities The candidate will use and develop methods within one, or multiple, of the following categories: Optical engineering, fluorescence