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Field
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uncover the critical metabolites and their genetic effectors, including receptors and metabolic enzymes, to reveal mechanistic insights of and identify key drug targets for hematologic malignancies
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the involvement of the immune system. Hands on experience in Western blotting, immunohistochemical staining, flow cytometry, enzyme-linked immunosorbent assays, etc. Hands on experience using rodent models
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, including pH-responsive and/or enzyme-responsive peptides for biomedical applications. Solid understanding of endosomal escape mechanisms and intracellular trafficking relevant to RNA delivery systems. A
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strategies (e.g. enzyme treatment, solid-state fermentation), to create fibrous, meat‑like structures that replicate bite, chewiness, and elasticity. Translate scalable solutions from upstream processing (e.g
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Researchers to join the Pellock Lab at GBI. The Pellock Lab, led by Principal Investigator Sam Pellock, focuses on the design and characterization of new enzymes to explore new chemistry, develop sustainable
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photometry approaches to systematically uncover the critical metabolites and their genetic effectors, including receptors and metabolic enzymes, to reveal mechanistic insights of and identify key drug targets
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: protein biochemistry, enzyme kinetics, coagulation assays, recombinant protein expression ● Molecular biology: gene expression analysis, RiboTag/RNA-seq, CRISPR, cloning ● Cell biology
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dynamics within computational models of cell-like crowded environments. Potential themes of research projects include enzyme dynamics, protein-misfolding and aggregation, and hemoglobin diseases. A doctoral
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; bioprospecting for novel microbial hosts, enzymes, and metabolites to support sustainable biomanufacturing. (Bio)pharmaceuticals: Processing science and technology for bio- and chemical transformations
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) validation and extension of models for the prediction of enzyme-substrate interactions; (iv) integration of the previous models into deep learning pipelines for retrobiosynthesis. Applicable legislation and