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Royal Netherlands Academy of Arts and Sciences (KNAW) | Wageningen, Provincie Gelderland | Netherlands | about 2 months ago
relationship between DNA methylation variants and gene expression. In a collaborative project between the Netherlands Institute of Ecology (NIOO-KNAW) and Utrecht University (UU), we will tackle these
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generations by establishing causal links between DNA methylation, gene expression, and inherited traits. It pioneers transient epigenome editing in a wild, non-model plant species. Your job To face climate
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methylation, DNA methylation and genetic risk markers for obesity originating from both human biomaterial and cell culture models to better understand the potential epigenetic mechanisms responsible for
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), microarray and DNA methylation analysis, with particular reference to genomics and population genetics studies. Skills are required in the analysis and interpretation of genomic data from modern
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and are known to be very strong gene regulators. Therefore, to avoid their harmful effects, in adult tissues they are silenced by epigenetic mechanisms such as DNA methylation. Dr. Horváth’s previous
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effects, in adult tissues they are silenced by epigenetic mechanisms such as DNA methylation. Dr. Horváth’s previous research has uncovered several mechanisms by which TEs regulate gene expression in
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, a methylation-aware tool that distinguishes mtDNA from NUMTs, overcoming short-read limitations. Analysis of 73 samples across 15 tissues enabled accurate genotyping and tissue-specific expression
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polymorphisms (Lahnsteiner et al. 2026) and DNA methylation (Lahnsteiner et al. 2024), altered during chronic inflammation. The project will analyze tissue-specific changes in G4 formation and epigenetic
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, RNA methylation, DNA methylation and genetic risk markers for obesity originating from both human biomaterial and cell culture models to better understand the potential epigenetic mechanisms
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, particularly how DNA methylation is written and remodeled on the human genome. The position is in close collaboration with Prof. Srigokul Upadhyayula to study the dynamics of DNA methylation enzymes in living