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research environment. What you would be doing You will be performing molecular and cellular biology experiments, including cell culture, CRISPR-based approaches, chromatin and gene expression analyses
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regulation of stem cell function in normal tissues and under abnormal conditions such as aging and cancer, and methods for editing stem cell genomes using CRISPR/Cas9 for experimental and therapeutic purposes
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cellular biology techniques, including nucleic acid manipulation, cloning, gene expression analysis, CRISPR-based approaches, protein analysis, and functional cellular assays. Extensive hands-on experience
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-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything
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combines allele-specific epigenomics, bulk and single-cell sequencing, viral vectors, and CRISPR-based in vivo editing. Candidates will work in a state-of-the-art, international research environment
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differentiating these stem cells into organ specific cell types and 3D organoids together with CRISPR technology, you will study how genetic variants shape cellular responses to chemical exposure. Combined with
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high-throughput sequencing to generate, analyze and integrate transcriptomic and epigenetic datasets To genetically (CRISPR/Cas9, shRNA) or pharmacologically (small molecules) perturb molecular targets
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instability and disease. The project offers extensive training in state-of-the-art approaches, including: CRISPR-based genome engineering quantitative high-content imaging and live-cell microscopy AI-assisted
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The International Institute of Molecular Mechanisms and Machines Polish Academy of Sciences | Poland | about 2 months ago
independently and as part of a collaborative, interdisciplinary research team Desirable Experience with mammalian cell culture Experience with CRISPR/Cas9 genome editing Experience with confocal microscopy and
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German Cancer Research Center in the Helmholtz Association (DKFZ) | Oettingen in Bayern, Bayern | Germany | 3 months ago
(4):584. Nature. 2026 Feb 25. doi: 10.1038/s41586-026-10187-2. By developing and applying genetic technologies for high-throughput applications in cells and mice, including CRISPR or transposon tools