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technologies aimed at assessing, protecting, and repairing donor livers before transplantation. This PhD project is embedded within the multidisciplinary CRISPR-CRYSTAL consortium, bringing together experts in
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How much does epigenetic variation contribute to rapid adaptation? This PhD at Utrecht University uses CRISPR/Cas9 and SunTag-based epigenomic editing in apomictic dandelions to test whether
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September 2026 Apply now How much does epigenetic variation contribute to rapid adaptation? This PhD at Utrecht University uses CRISPR/Cas9 and SunTag-based epigenomic editing in apomictic dandelions to test
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-on-brain.eu/ ). You will employ techniques such as organoid cultures (pluripotent stem cell and tissue-derived), transcriptomic analyses, CRISPR-Cas engineering, and other state-of-the-art tools. Your
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differentiating these stem cells into organ specific cell types and 3D organoids together with CRISPR technology, you will study how genetic variants shape cellular responses to chemical exposure. Combined with
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renowned virologist and one of the pioneers of the CRISPR-Cas technology, which works by cutting a DNA sequence at a specific genome location and deleting or inserting genes there. The CRISPR-Cas method