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Field
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, Mathematics, Physics, Computer science, or a related field. Prior experience in integrating diverse datasets and developing computational tools for data analysis and Interest in designing and implementing
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PhD Studentship - Extending the Chemical Space of mAb Based Cancer Treatment with DNA Nanostructures
drugs with limited toxicity in patients. There are 3 objectives: 1) Design and synthesis of a simplified and stable DNA nanopore, 2) synthesis of a cleavable linker for attachment to the immune
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very challenging. Therefore, high-throughput screening of drug-like molecules needs to also consider their synthetic viability. The aim of this project is to develop a deep learning and generative design
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this inspiring environment our rich diversity of research groups, several of international prominence, develop and conduct work of great scientific importance. Among our core competencies are computational
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this inspiring environment our rich diversity of research groups, several of international prominence, develop and conduct work of great scientific importance. Among our core competencies are computational
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modelling of proteins (e.g. receptors), protein structure prediction, computer-aided drug design, molecular docking, machine learning, and scientific programming is preferred, but not required. Rules
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Experience in modelling of proteins (e.g. receptors), protein structure prediction, computer-aided drug design, molecular docking, machine learning, and scientific programming is preferred, but not required
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candidate will be responsible for conducting research on novel drug delivery methods to target cancer cells. This will involve designing and performing experiments, analyzing data, and presenting findings
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design of molecular interactions. The project will specifically be related to the 3D structure of proteins and other molecules such as pharmaceuticals and the prediction of interactions between these. A
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achieving reliable cell penetration. Unlike Lipinski’s 'rule of five' which can guide small molecule drug design, there is currently no defined set of rules for developing peptide drugs. The aim