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German Cancer Research Center in the Helmholtz Association (DKFZ) | Heidelberg, Baden W rttemberg | Germany | 3 months ago
breaks, copy-number alterations, and other structural genome changes. Our group combines cutting-edge genome biology approaches with quantitative, multi-omics analyses to uncover the mechanisms
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, visualization, rendering, modeling, interaction, simulation, game technology, and immersive environments, with strong connections to artificial intelligence, data science, AR/VR, 3D computer vision, and high
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the cell wall middle lamella is progressively degraded, weakening the adhesion between cells. This PhD project aims to build a multiscale computational model linking molecular-level pectin breakdown to whole
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of selected heat integration or thermal energy storage concepts Modelling and preliminary sizing of heat exchangers and thermal energy storage components Simulation and comparison of selected system layouts
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computational biology company. The project focuses on understanding patient responses to drug treatments through multiomic analyses, including chromatin profiling, single-cell sequencing, and spatial
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. Assists in the daily use and maintenance of specialized equipment in the laboratory including spectrophotometers, incubators, FACS machines, cell culture equipment micro-injection apparatuses, regular and
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researchers with diverse skill sets and a common interest in elucidating the extrinsic and intrinsic signals that regulate stem cell behaviour. The Spagnoli lab is a highly dynamic team, doing exciting science
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second study involves collaborating on tiered studies using cell culture, ex vivo and in vivo approaches to evaluate the toxicity of toxins (especially neurotoxins) and to assess the efficacy
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: Develop and optimize multistep synthetic routes for new small molecule fluorophores and bioactive ligands for multimodal microscopy applications. Apply drug-discovery models, molecular docking simulations
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(KCL), the post holder will investigate the biology of regulatory T cells (Tregs) to identify the most suppressive Treg subsets within IBD gut lesions - informing targeted strategies for restoring immune