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: Develop and optimize multistep synthetic routes for new small molecule fluorophores and bioactive ligands for multimodal microscopy applications. Apply drug-discovery models, molecular docking simulations
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programmed cell death using the nematode roundworm Caenorhabditis elegans (C. elegans ). The team uses genetic, molecular, cell biological, and behavioral approaches. More information can be found
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to chromosome structure in cell nuclei and biochemical reconstitutions. This involves developing supervised and self-supervised AI models based on simulated as well as annotated experimental cryoET data, informed
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