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supporting professional growth and interdisciplinary collaboration. Be Bold. Join a laboratory pioneering the use of bioengineered human muscle systems, known as myobundles, to investigate the mechanisms
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to investigate the mechanisms that drive the malignant transformation of colorectal adenomas into colorectal cancer. These positions are supported by a recently funded NIH R01. The project addresses an important
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program focused on understanding epigenetic and transcriptional mechanisms that regulate cellular responses in cancer, inflammation, and other diseases. The candidate will contribute to ongoing projects
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. The project focuses on developing and applying single-cell multi-omics approaches to uncover regulators acting upstream of known epigenetic writers and erasers during embryonic development. Expected start date
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, define their developmental cell(s)-of-origin and uncover mechanisms underlying the striking sex differences observed in these tumors. Your work will combine various -omic techniques, such as Hi-C, long
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of disrupting translocation biogenesis without compromising normal cell function. This Cancer Research UK (CRUK)-funded project aims to investigate the molecular mechanisms by which early RT cis-regulatory
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, electrical polarisation and, then evaluate cell-matrix interactions using live-cell imaging, molecular assays and, spatial transcriptomic approaches to identify key mechanisms linking matrix mechanics
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candidate will have a strong background in experimental cell biology, molecular biology, or a related field, with a particular interest in understanding molecular mechanisms of cellular regulation. Hands
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imaging, high-content, single-cell resolution) to assay compound activity Develop imaging assays capable of distinguishing mechanism of action (e.g. growth inhibition, biofilm/attachment disruption
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to submitting your application, please review and update (if necessary) the information in your candidate profile as it will transfer to your application. Job Title: Post Doctoral Scholar - Physiology & Cell