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neuronal circuits requires the coordinated execution of several developmental processes, including neuronal migration, axon growth and guidance, and synaptogenesis. These processes critically depend
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and the Ascidian Ciona to understand the molecular, cellular and neuronal mechanisms of pressure sensation. The comparative analysis will require the use of high-end techniques in neurobiology including
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patient-derived organoids. •Co-culture of glioblastoma cells with various components of the tumour microenvironment, including neurons and astrocytes derived from iPSCs or isolated from mouse models
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cellular changes. Advanced imaging techniques, including structural and functional-MRI, developed by Dr. Emmanuel Barbier (GIN director), will be used to optimize rSynES and monitor neuronal changes over
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synaptic behavior for neuromorphic computing. Artificial neurons can also be constructed using antiferroelectric tunnel junctions. However, antiferroelectrics like PbZrO3 are complex materials
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multicolor fluorescence labeling of mouse neurons according to their cell lineages. The team is currently pursuing the improvement of the technology and exploring novel applications. Objectives: A first
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autophagic pathways. Using advanced imaging, cell biology, and biochemical approaches in human iPSC-derived astrocytes and neuronal models, the project will characterize the molecular mechanisms linking
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, particularly along invasion routes enriched in neurons, oligodendrocytes and myelin-derived material, and may shape metabolic programs that support tumour dissemination and resistance. Understanding
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all jawed vertebrates for motor coordination and higher cognitive functions. Cerebellar neurons arise from two main germinative zones: the ventricular zone and the upper rhombic lip (URL), a specialized
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, including researchers, faculty members, engineers and technicians, as well as non-permanent staff, including fixed-term contract researchers, postdoctoral researchers, PhD students and interns, distributed