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measures across multiple zebrafish models of leukodystrophy, including models of RNASET2 deficiency, adrenoleukodystrophy (ALD), Krabbe disease and metachromatic leukodystrophy (MLD). Zebrafish are widely
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brain circuits, but the role of protein synthesis in this key developmental process is still poorly understood. Using zebrafish and mouse models, this project will compare ribosomes in progenitors and
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. In this project we will study the functions of the rare coding variants using zebrafish and compare the results with mouse models of equivalent mutations and human post-mortem brain tissue
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