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. You will use human in vitro models, including astrocytes and brain organoids generated from induced pluripotent stem cells (iPSCs) of people with MLC and healthy controls. You will investigate disease
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basis for the potential testing of future therapeutic strategies. We are seeking a highly motivated and intellectually curious PhD student, ideally with strong background in cell culture and biochemistry
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of Michigan in the Department of Cell & Developmental Biology (CDB). We use a combination of developmental biology models including Xenopus (frog), mouse, and pluripotent stem cells, gene editing, and
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the vascular organoid model, to establish a causal link between these target genes and the vascular calcification phenotype. This PhD project, at the interface of vascular biology, immunology, stem cell biology
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drivers of this IFN-mediated neuropathology using conditional in vivo expression of the pathogenic allele in individual cell types, allied with human induced pluripotent stem cell (hiPSC) models
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be awarded a PhD) in Biophysics or a related field and have extensive experience with stem cell and gastruloid cultures, imaging and image analysis, as well as developing assays for biophysical
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Columbia University Irving Medical Center / Vagelos College of Physicians and Surgeons | New York City, New York | United States | about 6 hours ago
Diabetes Center, Columbia Stem Cell Initiative, and the Taub Institute, and have the opportunity to interact with faculty at Columbia University’s Morningside and Manhattanville Campuses.
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Johns Hopkins Medicine - Laboratory of Human Biomimetics | Saint Petersburg, Florida | United States | about 1 month ago
-cell biology, immune activation, or immune tolerance Hematopoietic stem cell transplantation or GVHD Mucosal, intestinal, hepatic, or systemic immunology Flow cytometry, cytokine profiling, or single
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pluripotent stem cells 3. Microscopy – immunofluorescence, confocal, wide-field, live cell 4. Microfluidics – bioengineering, device preparation, input/output bioanalysis 5. Genome editing – guide RNA
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alterations that promote tumor initiation and progression. Building on these studies, we have expanded our research to explore the roles ofmetabolism and autophagy in embryonic and cancer stem cell biology