3 solid-oxide-cells Postdoctoral positions at Heidelberg University in computer-science
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have generated extensive comparative genomics datasets (e.g., single-cell RNA-seq and ATAC-seq) across species, based on samples from our unique organ collections, and analyzed them using state
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. Mutations and deletions of NR2F1 lead to Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS). Using neuronal cells derived from CRISPR/Cas9 engineered human induced pluripotent stem cells (hiPSC) we model
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of single-cell multi-omics data (scRNA-seq, scATAC-seq, Multiome) to reconstruct gene regulatory networks in 3D forebrain dorsal organoids to determine pathophysiological consequences of aberrant NR2F1 dosage
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