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arrest, DNA repair, senescence, and apoptosis. However, targeted induction of p53 by small molecule inhibitors of a key upstream negative regulator MDM2 leads in most cancer types to a reversible
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 2 months ago
. Position Summary THESE ARE TIME - LIMITED POSITIONS WITH AN ESTIMATED DURATION OF 2 YEARS . Our research lab is developing small molecule and gene therapies for Angelman syndrome, Pitt-Hopkins
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biophysical and structural approaches, including NMR, X-ray scattering, cryo-electron microscopy, advanced microscopy, single-molecule methods, and molecular and cellular biology. The PhD student will
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the operation of the Novel and Compound Glass equipment. This equipment is employed in fabricating materials from as thin as a single molecule to as thick as several millimetres. It includes gloveboxes
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-microscopy, biophysics, single molecule tracking and force spectroscopy, micro/nanofluidics, electron microscopy, scanning probe microscopy, biosensors and bioelectronics, biomedical devices, bioengineering
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cellular or immune therapies, small-molecule therapeutics, or other innovative treatment strategies grounded in rigorous mechanistic studies of brain tumor biology. Appointment will be in the Division
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a new project in the lab of Professor Heath Murray, looking at single-molecule dynamics of the replicative helicase in the model bacterial organism Bacillus subtilis . The aims are to develop methods
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and single-molecule genomics analysis Spatial omics and image-free or sequencing-based imaging analysis Multi-modal data integration across single-cell, spatial, and bulk assays Probabilistic and
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computational tools to analyse single molecule nanopore sequencing data with a focus on RNA modifications. Key methods in nanopore sequencing and computational modelling have been established in the group
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its usage. analytics About this tool (Opens in a new window) Skip to main content Fully-funded PhD Studentship: Single-cell spatial multi-omics for cancer biology University of Cambridge - Cancer