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, and continue to advance, a set of untargeted and targeted spatial, single-cell, single-nucleus, and perturbational omics technologies. Our in vivo single-cell CRISPR technologies allow us to screen for
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important targets in modern medicine. Despite major advances in kinase inhibitor development, many regulatory mechanisms remain poorly understood, particularly those involving allosteric and non-catalytic
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and to identify novel pathways and targets for disease‑modifying therapies. About the role We are seeking to recruit a postdoctoral researcher to establish an iPSC biobank for Alzheimer’s disease
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and to identify novel pathways and targets for disease‑modifying therapies. About the role We are seeking to recruit a postdoctoral researcher to establish an iPSC biobank for Alzheimer’s disease
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project leadership experience in small-molecule discovery and expertise to help guiding a diverse portfolio of programs spanning different target classes and therapeutic areas. The role sits
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comprehensive proteome profiling including mapping of protein modifications to targeted quantification, protein interaction mapping, low-input and chemical proteomics. Throughout the process—from sample
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acquire their fate and establish precise connectivity with target brain regions during development, and how these processes are altered by stress and pathology. To address these questions, the team combines