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this project, single-cell and/or spatial transcriptomics approaches in aortic tissue samples of transgenic TAAD mouse models will be used to further unravel the disease processes and to identify potential
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-regulatory network analysis approaches, developed and employed in the Malysheva Lab, are required to reveal these mechanisms. With the proposed project we aim to bridge this gap in our knowledge of cis
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spatial analysis in the same organs using multiplex immunofluorescence and spatial transcriptomics. We are convinced that this project will get us one step closer in our understanding of chronic lung
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spatial transcriptomics data analysis. Experience in the field of cardiovascular diseases is considered a plus. What we offer We offer a doctoral scholarship for a period of four years, upon positive
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mutations. Therefore, an integrative genome-wide cis-regulatory network analysis approaches, developed and employed in the Malysheva Lab, are required to reveal these mechanisms. With the proposed project we