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cell biological and biophysical characterization of various alpha-synuclein aggregates/oligomers found in vivo (Mouse models and human tissue) that can induce neuropathology/neurodegeneration. 1
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University of California, Los Angeles | Los Angeles, California | United States | about 2 months ago
Skip to main content Recruit Home Open Recruitments Chemical and Biomolecular Engineering: Postdoctoral Employee - in vivo cell engineering (JPF11226) Chemical and Biomolecular Engineering
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lung fibrosis. The ideal candidate will independently perform studies utilizing established in vitro, ex vivo and in vivo preclinical models and will have the opportunity to develop and refine novel
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in Medicine and Surgery or equivalent. Doctoral degree in the area of Biomedical Sciences. Twelve months of experience in research with perfusion, preservation or maintenance of ex vivo organs in
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of toxicology. Experience in cell culture, mouse handling, in vitro/in vivo exposures, and basic molecular biology techniques such as western blot, RT-PCR, flow cytometry, etc. is beneficial. A background in lung
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expression and those critical for the pathogen's intracellular survival in vivo and in vitro. Position(s) will also be actively involved in the project to define axinic media culture development of E
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of phosphoinositide 3-kinase (PI3K) signaling in allergy, metabolic control, obesity, diabetes and cancer; see https://p3.snf.ch/project-189065 ii) developing and validation of novel chemical probes and degraders
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-areal communication in the brain. We use a combination of in vivo calcium imaging and Neuropixels recordings as well as computational modelling techniques. The department is embedded in the vibrant
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region in the IGH enhancers. Next, hit compounds will be validated for their effect on lymphoma cell growth and potential toxicity towards normal cells. Finally, selected compounds will be assessed in vivo
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Quantitatively analyze transport, partitioning, and binding kinetics in biological matrices Conduct and contribute to in vivo studies in musculoskeletal models Independently write and publish high-impact