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a small fraction of the sample voxels need to be re-measured to detect the change, rather than the complete 3D volume. Microchip samples are also highly structured, with known design rules, which can
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a small fraction of the sample voxels need to be re-measured to detect the change, rather than the complete 3D volume. Microchip samples are also highly structured, with known design rules, which can
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. This allows us to shift from the standard imaging question of "what is the structure of this sample?" to "how does the structure differ from the known design?". The second question can be answered with far
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statistical reasoning, including a clear understanding of model assumptions, uncertainty, validation, data structure, and the limitations of different analytical approaches. Experience with multimodal human