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epigenetic editing delivered via lipid nanoparticles; Using a combination of cell models and human donor livers, you will investigate how these technologies can improve organ quality and increase the number
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The importance of oxide nanoparticles spans from fundamental astronomy (e.g. nanosilicate dust particles) to applied catalysis (e.g. photoactive TiO2 and electroactive IrO2 nanoparticles). Across these fields
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Your position This project addresses that limitation by designing ultrasmall nanoparticles suitable for intravenous delivery and tumor targeting, with a specific focus on neuroblastoma. Building
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of at least one would be essential: • Mxenes containing magnetic nuclei. • Metal organic framework derived carbon supported magnetic nanoparticles. • Large unit cell magnetic
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isolation; electron microscopy and nanoparticle tracking analysis for vesicle characterization; RNA isolation and PCR; SDS-PAGE-based protein analysis; cell culture and immunostimulation experiments; and flow
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to support newborn-screening follow-up and monitoring of emerging therapies, including gene and lipid-nanoparticle therapies. Planned secondments will provide experience in omics data generation and biomarker
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Offer Description The ROMEO project seeks to overcome a major hurdle in nanomedicine: the fact that less than 1% of current nanoparticles reach their target because they are captured by macrophages in
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secondments will broaden your expertise through hands-on training in lipid nanoparticle delivery. You will also have opportunities to engage with patients and families to better understand leukodystrophies and
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closely connected within the research team. The resulting biomarker panel will aim to support newborn-screening follow-up and monitoring of emerging therapies, including gene and lipid-nanoparticle
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. The position is part of a newly funded Wellcome Leap Focused Antibiotics project developing nanoparticle-mediated antibiotic delivery systems for site-directed treatment of infection while protecting the gut