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involvement across the 3 work packages (snRNAseq, vascular organoids, CRISPR validation). Chronic kidney disease (CKD) affects around 10% of the world's population and drives major vascular remodeling
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for molecular imaging and targeted therapies. However, their clinical translation is often limited by unfavorable pharmacokinetic properties, including rapid blood clearance and high kidney uptake. This project
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developing innovative siRNA‑based therapies. Our research focuses on areas with high unmet medical need, including cardiovascular, metabolic, liver, and kidney diseases. We have access to a strong and
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