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/exosomes. Advanced cell culture, molecular biology and imaging approaches will be combined to study cellular responses and mechanisms relevant to oral disease and regenerative medicine. The overall aim is to
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biomaterials, development of wear-testing methods, crown-material processing, mechanical characterisation, surface characterisation, micro-CT and quantitative image analysis. An interdisciplinary and
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extracellular vesicles/exosomes. Advanced cell culture, molecular biology and imaging approaches will be combined to study cellular responses and mechanisms relevant to oral disease and regenerative medicine
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of algorithms for medical image analysis. The successful candidate will investigate computational complexity, stability, and numerical summaries of multiparameter persistence, as well as applications to medical
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applications to medical data. The project will combine theoretical work on multiparameter persistence with the design and implementation of algorithms for medical image analysis. The successful candidate will
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progression. Using image-based siRNA screens, we have identified novel regulators of ER-phagy. This project aims to investigate the molecular mechanisms of ER-phagy and how this contributes to cancer
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transcriptomics or proteomics, multiplexed imaging and/or integration of spatial transcriptomics with single-cell RNA-sequencing datasets. Experience from relevant research projects will be considered an advantage
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field high-speed microscopic imaging Experience with control and synchronization of high-speed imaging and lighting systems Experience with image post-processing and data extraction Personal
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to cancer progression. Using image-based siRNA screens, we have identified novel regulators of ER-phagy. This project aims to investigate the molecular mechanisms of ER-phagy and how this contributes
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of maturity, this technology requires to experiment a change of paradigm to guarantee a sustainable development for the years to come. One pathway to achieve this paradigm shift relies on the development