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Field
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. The project will be focused on addressing several challenges in structure-based drug design using artificial intelligence. Recently developed techniques for the prediction of the three-dimensional
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the drug discovery process. The project will be focused on addressing several challenges in structure-based drug design using artificial intelligence. Recently developed techniques for the prediction
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very challenging. Therefore, high-throughput screening of drug-like molecules needs to also consider their synthetic viability. The aim of this project is to develop a deep learning and generative design
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. Professorship in Pathogen Evolution (ETH Zurich and Eawag) is seeking a highly motivated PhD Candidate to study drug resistance evolution in various pathogens through population genetic modelling and
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PhD Studentship - Extending the Chemical Space of mAb Based Cancer Treatment with DNA Nanostructures
drugs with limited toxicity in patients. There are 3 objectives: 1) Design and synthesis of a simplified and stable DNA nanopore, 2) synthesis of a cleavable linker for attachment to the immune
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efficiency, drug resistance, high toxicity, long duration of treatment, relapse, inconvenient and painful injections, and the cost. To overcome these limitations, in this project we will employ metal organic
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products through empirical work underpins the process design of most commercial batch granulation processes. This consumes many batch runs, plant time and input materials for new drugs and new process lines
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modelling and simulations, PKPD, in vitro ADME models, advanced in vivo methods, development of biological medicines, as well as patient and societal aspects, from optimizing the use of drugs in individuals
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modelling and simulations, PKPD, in vitro ADME models, advanced in vivo methods, development of biological medicines, as well as patient and societal aspects, from optimizing the use of drugs in individuals
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of other excipients such as polymers or lipids for enhancing drug dissolution rates with improved stability Physicochemical characterizations of extrudates Employment of Quality by Design (Qbd) and Process