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imaging, high-content, single-cell resolution) to assay compound activity Develop imaging assays capable of distinguishing mechanism of action (e.g. growth inhibition, biofilm/attachment disruption
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materials collectively determine their macroscopic interface response. The work will connect cell-scale mechanics with concepts from multiscale/rough-surface contact mechanics to develop effective
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to dissect mechanisms of adverse effects in cancer and metabolism. For a summary of the latter see: https://p3.snf.ch/project-204602 Application Please submit your resume (CV), a letter of motivation, a
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stress over time—is a defining mechanical feature of most native soft tissues and is increasingly recognized as a critical regulator of cell behavior including proliferation, differentiation, and migration
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solution while maintaining mechanical stability, and characterize the thermal and chemical stability of components and formulations. You will apply in-situ diagnostics, in particular in-flow UV-Vis
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, intracellular trafficking and transport, and mechanisms of quality control and cellular homeostasis. The new professor will investigate biological systems at the cell, tissue and/or (model) organism level
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, diabetes and cancer; see https://data.snf.ch/grants/grant/189065 ii) developing and validation of novel chemical probes and degraders to dissect mechanisms of adverse effects in cancer and metabolism. For a
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to identify the physical principles and cell biological mechanisms underlying the continuum properties of living matter. We are an interdisciplinary group and welcome researchers from diverse backgrounds
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standard biological assays (cell viability, immunostaining, gene/protein expression); mechanical characterization of soft materials (rheology, compression testing); or live-cell imaging and image analysis
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optical technologies to study mechanisms of cell surface signaling, cancer neuroscience, and protein engineering, integrating molecular biology, cell biology, and systems neuroscience approaches. To support