STI – PhD position in single-molecule imaging and manipulation of membrane-less organelles (MLOs)

Laboratory of Nanoscale Biology at the Ecole Polytechnique Fédérale de Lausanne (EPFL) has an opening for a doctoral student to investigate the behavior of individual molecules and biomolecular phase transition in vitro and in living cells. The successful candidate will work independently to develop and drive forward his/her research project and also collaborate on ongoing projects in the group.

You will use single-molecule imaging and advanced computational methods developed by our lab to visualize and quantify the dynamics and biophysical properties of membrane-less organelles (MLOs). Our state-of-the-art imaging platforms (SMLM/SIM/SOFI) are combined with commercial or homemade optical tweezers and scanning probe microscopes.

To apply, please send your complete application in a single PDF file, including a cover letter, full CV including publication list and the contact information of 3 referees, to [email protected]

Submitted applications will be evaluated immediately, and the search will remain open until the position is filled.

Your qualifications
We want to recruit a candidate who is familiar with any of the following topics:

• Prior backgrounds in optical tweezers, scanning probe microscopy, single-molecule FRET, as well as single molecule imaging in live mammalian cells are highly desired
• Excellent knowledge of optical design, image and computational analysis
• The ability to work effectively in a team and possess good communication skills

We are looking for independent, creative and highly motivated scientists interested in exploring biophysical principles governing the function and regulation of cellular phase transitions.

We offer :

The EPFL is located in Lausanne – Switzerland, has a highly international environment, state-of-the-art facilities, a track record in the incubation of successful biotechnology companies, and is consistently ranked among the world’s top institutions in scientific research. Lausanne is a lively and cosmopolitan urban center located in a unique natural setting with great outdoor activities. Salaries and benefits are internationally competitive.

The successful candidate will join a vibrant collaborative, international and diverse research team. More information about the research themes can be found on the following link : https://www.epfl.ch/labs/lben/  

Start date : The position is immediately available

Term of employment : Fixed-term (CDD)