PhD position: In vivo gene editing and functional genomics to interrogate brain development and function
27 Feb 2024
Job Information
- Organisation/Company
ETH Zurich- Department
Department of Biosystems Science and Engineering- Research Field
Biological sciences » Biological engineering
Neurosciences » Neurobiology
Biological sciences » Biology- Researcher Profile
First Stage Researcher (R1)- Country
Switzerland- Application Deadline
18 Mar 2024 - 12:00 (Europe/Zurich)- Type of Contract
Not Applicable- Job Status
Full-time- Offer Starting Date
15 Aug 2024- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The Laboratory for Biological Engineering (Prof. Randall J Platt) of the ETH Zurich in Basel, Switzerland develops genome engineering technologies and applies them to a range of fundamental and disease-focused areas. To advance these efforts, the Platt group is recruiting a full-time (100%) PhD Student to develop and apply in vivo functional genomic methods.
Project background
Investigating gene function using direct in vivo screening is revolutionising the way we study brain biology . We have previously developed AAV-based molecular methods for direct in vivo CRISPR screening and are continuing to develop novel tools to be able to interrogate new aspects of brain biology.
Job description
We are looking for a highly motivated and collaborative researcher to be integrated in a multidisciplinary team of scientists. The candidate will develop novel molecular methods and apply them to ask fundamental questions about brain development and function in the context of health and disease. The candidate will be passionate about science, technology, collaboration, and communication.
Requirements
- Research Field
- Biological sciences
- Education Level
- Master Degree or equivalent
Skills/Qualifications
The ideal candidate should have a Master’s degree or equivalent in Biology, Neurobiology, Molecular Biotechnology, Molecular Medicine, or a related field. The successful candidate will have experience across several of the following areas:
- cloning, molecular biology techniques and synthetic biology
- virus production and/or evolution and delivery (AAV, LV)
- in vivo interrogation of mouse models, including histological techniques, imaging and quantification
- primary cell isolation, cell culture, and flow cytometry
- preparation of deep sequencing libraries for functional genomics experiments
- bioinformatics, statistics, and programming
The candidate must have a strong motivation and interest in collaboration with multi-disciplinary scientists. They must be able to communicate effectively in a highly interdisciplinary and international environment, which includes a mastery of oral and written English as well as scientific illustration using Adobe Illustrator or equivalent.
- Languages
- ENGLISH
- Level
- Excellent
Additional Information
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- ETH Zurich
- Country
- Switzerland
- Geofield
Where to apply
- Website
https://jobs.ethz.ch/job/view/JOPG_ethz_Kgz5zLZNDVvY0Jllhw
Contact
- State/Province
Basel-Stadt- City
Basel- Website
https://bsse.ethz.ch/platt- Street
44 Schanzenstrasse- Postal Code
4056
STATUS: EXPIRED
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