PhD position - Development of cellular model platforms to study IgG light chain toxicity of oncohematological diseases

Updated: 2 months ago
Job Type: FullTime
Deadline: 16 Apr 2024

15 Feb 2024
Job Information
Organisation/Company

Pavol Jozef Šafárik University in Košice
Research Field

Physics » Biophysics
Biological sciences » Biological engineering
Chemistry » Biochemistry
Researcher Profile

First Stage Researcher (R1)
Country

Slovakia
Application Deadline

16 Apr 2024 - 00:00 (Europe/Bratislava)
Type of Contract

Temporary
Job Status

Full-time
Hours Per Week

37,5
Offer Starting Date

1 Sep 2024
Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Embark on a groundbreaking PhD project that aims to advance our understanding of oncohematological diseases, particularly multiple myeloma and its associated IgG light chain variants. This research is crucial for unraveling the mechanisms behind the tissue-specific toxicity of these pathological forms. You will utilize a blend of cellular biology, bioengineering, and biotechnology techniques in developing these platforms, enabling a detailed analysis of variant-specific toxic effects. This research holds the potential to significantly enhance our understanding of the tissue-specific toxicity of IgG light chain variants in multiple myeloma, opening pathways to more effective treatments. As a PhD candidate, you will be at the forefront of this innovative research, collaborating with esteemed international researchers, including Dr. Magdaléna Harakalová from the Circulatory Health Research Centre in Utrecht, Netherlands. This partnership offers a rich environment for scientific growth and international networking.

Project goals:

1) Develop innovative cellular platforms to assess the toxicity of various pathological IgG light chain variants found in different patients.

2) Design of an analytical chip for various cellular platforms.


Requirements
Research Field
Biological sciences » Other
Education Level
Master Degree or equivalent

Research Field
Chemistry » Biochemistry
Education Level
Master Degree or equivalent

Research Field
Physics » Biophysics
Education Level
Master Degree or equivalent

Languages
ENGLISH
Level
Excellent

Additional Information
Work Location(s)
Number of offers available
1
Company/Institute
University PJ Safarik in Kosice, Slovakia
Country
Slovakia
Geofield


Where to apply
E-mail

[email protected]

Contact
City

Košice
Website

https://www.upjs.sk/
Street

Šrobárova 2
Postal Code

O41 80
E-Mail

[email protected]

STATUS: EXPIRED

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