PhD Student: DSMBBC/2023/24 Identification of key structural elements of immunomodulatory proteins - inhibitors of antigenic peptide transporter TAP encoded by selected alphaherpesviruses

12 Jan 2024
Job Information

Organisation/Company

Institute of Biochemistry and Biophysics Polish Academy of Sciences

Department

Biological NMR Facility

Research Field

Biological sciences » Other

Researcher Profile

First Stage Researcher (R1)

Country

Poland

Application Deadline

29 Jan 2024 - 00:00 (Europe/Warsaw)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

40

Offer Starting Date

1 Mar 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Structural analysis of the peptides comprised various fragment of the Herpes simplex virus 1 (HSV-1) in solution and phospholipids utilizing multidimensional heteronuclear NMR spectroscopy. The studies will be performed on the two NMR spectrometers installed in Laboratory of Biological NMR (FA-05). The structural studies required preparation different variants of the peptides included 15N- and 19F-labeled residues. Multidimensional experimental data sets acquired for 15N or/and 19F resonances will be used as input for resonance assignments and structure calculations of peptides in DPC / SDS micelles or phospholipids. In addition, molecular dynamic processes will be studied based on 15N and 19F relaxation data.

Requirements

Research Field

Biological sciences

Education Level

Master Degree or equivalent

Skills/Qualifications

Holding a degree of Master of Science [Magister], Master of Engineering [Magister Inżynier], medical doctor or equivalent in the field of: exact sciences, natural sciences, medical sciences or related disciplines, granted by a Polish or foreign university; a person who does not possess the qualifications described above may take part in the competition, but must obtain the qualifications in question and provide the relevant documents before the start of the programme at the Doctoral School (i.e., March 1, 2024). Education at the Doctoral School begins on March 1 2024.

Some knowledge about NMR spectroscopy and other spectroscopic methods in biomolecular studies.

 

Level

Good

Additional Information
Benefits

Scholarship amount (net, PLN, monthly):
1st year: 4000 (approximately); 2nd year: 4000 (approximately); 3rd year: 4500 (approximately); 4th year: 4500 (approximately)

Selection process

The recruitment process consists of two stages:

a) selection of candidates by the Committee based on their previous achievements and academic performance presented in the documents submitted; for each position no more than 5 applicants who have achieved the highest scores, but no less than 60% of the maximum points, shall be qualified for the next stage;

(Selected candidates will be invited for the interview that will take place from 22/01/2024 to 26/01/2024 (the exact date will be given in the invitation)).

b) an interview conducted by the Committee including in particular:
• a presentation delivered by the candidate containing the outcomes of his/her research (a Master’s thesis or other research work carried out by the candidate); the presentation must not last longer than 10 minutes;
• questions asked by the members of the Committee related to the presented project, the methods used and interpretation of the results obtained;
• questions asked by the members of the Committee related to the proposed PhD programme described in the recruitment announcement;
• questions related to the candidate’s motivation for scientific work.

Additional comments

Required documents:
a) an application for admission to the Doctoral School, together with consent to the processing of personal data for the recruitment procedure and a statement on familiarising oneself with recruitment rules and conditions; (You can find the form here: https://ibb.edu.pl/en/phd-studies/rekrutacja/ )

b) a copy of the diploma from a university or the candidate’s statement on the estimated graduation date;

c) a scientific curriculum vitae including information on the candidate’s participation in scientific projects and other related activities, such as publications, involvement in science club, participation in academic conferences with an oral or poster presentation, national and international internships, prizes and awards, participation in grants, popularization of science, voluntary work;

d) a list of completed university courses with marks;

e) a motivation letter;

f) contact details to at least one academic adviser or academic staff member holding at least a doctor’s degree, who has agreed to give an opinion on the applicant. The opinion should not be attached to the application;

g) in the case of having a disability certificate or a certificate on the degree of disability, or a certificate referred to in Article 5 and Article 62 of the Act of 27 August 1997 on Vocational and Social Rehabilitation and Employment of Persons with Disabilities ‒ a statement of holding such certificate;

h) candidates holding a diploma of completing studies abroad shall additionally attach a certified translation of the diploma, including the supplement, into Polish or English, unless the diploma or an official copy thereof, including the supplement, has been issued in English.;

Website for additional job details

https://ibb.edu.pl/en/phd-studies/rekrutacja/

Work Location(s)

Number of offers available

1

Company/Institute

Institute of Biochemistry and Biophysics Polish Academy of Sciences

Country

Poland

State/Province

Mazovia

City

Warsaw

Postal Code

02-106

Street

ul. Pawińskiego 5a

Where to apply

Website

https://ibb.edu.pl/en/phd-studies/rekrutacja/

Contact

State/Province

Mazovia

City

Warsaw

Website

https://ibb.edu.pl/en/phd-studies/rekrutacja/

Street

ul. Pawińskiego 5a

Postal Code

02-106

E-Mail

[email protected]

STATUS: EXPIRED