7 molecular dynamics simulation positions at The Netherlands Cancer Institute in Netherlands
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an explanation for the observed dynamics in the expression of tRNA genes. In this collaborative project, we will investigate the mechanisms of tRNA gene regulation using novel methods and technologies in human
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specifically, we aim to identify new factors and molecular mechanisms that are critical in telomere and genome maintenance through appropriate DNA damage responses, DNA replication, and DNA repair. In
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passionate and driven PhD candidates to join our dynamic research team full time and on location in Amsterdam in July 2024. The successful applicants will play a pivotal role in executing the EFPN’s research
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analysis tools in both yeast and mammalian model systems. By studying transcription dynamics in single cells, we aim to elucidate the molecular mechanisms of transcription regulation. Requirements Specific
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cells (Bartok et al., Nature 2021; Champagne et al., Molecular Cell 2022; Pataskar et al., Nature 2022; Yang., Molecular Cell 2024). In a project awarded by ERC-AdG-2024 for five years, the Agami group
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) ATACseq, ChIPseq and more to catalogue molecular changes at the genome-wide level following perturbations. We use acute protein depletion of key regulatory factors to determine the direct targets of a
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research (for instance gene transfer, embryology, and molecular cloning) Excellent communication and teamwork skills. Ability to work independently and as part of a team. Fluency in English. Additional