Postdoc vacancy in the research group of Elzo de Wit

14 Feb 2024
Job Information

Organisation/Company

The Netherlands Cancer Institute

Research Field

Medical sciences
Physics

Researcher Profile

Recognised Researcher (R2)

Country

Netherlands

Application Deadline

12 Apr 2024 - 21:59 (UTC)

Type of Contract

Temporary

Job Status

Not Applicable

Hours Per Week

36.0

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Research group

The lab uses genomics methods such as Hi-C, (single cell) RNAseq, TTseq, (single cell) ATACseq, ChIPseq and more to catalogue molecular changes at the genome-wide level following perturbations. We use acute protein depletion of key regulatory factors to determine the direct targets of a specific factor to understand the mechanistic role of these factors (Maresca et al. 2023, EMBO Journal). The candidate will mechanistically dissect the role of the cohesin complex in gene regulation in mouse embryonic stem cells and embryo models.

Responsibilities

We are looking for a candidate that will develop an independent research line to elucidate the role of cohesin in gene regulation. In this context, the applicant will be responsible for establishing models that will enable the genome-wide dissection of the role of cohesin in gene regulation. We expect the successful applicant to have direct interactions with other computational and experimental researchers, to supervise PhD and undergraduate students, present and communicate scientific results and to be involved in the writing of scientific papers.

Requirements
Specific Requirements

The de Wit lab seeks to recruit an ambitious postdoc with a strong background in molecular biology and a strong commitment to science. You are expected to also coach and guide other members of the team. The lab also hosts a sizeable number of computational biologists, therefore an affinity with large data and bioinformatics is a prerequisite.

In particular, we seek candidates with the following molecular biology skills;

• Experience with CRISPR genome editing.
• Experience with or willing to learn genomics methods (RNA-seq, ATACseq, Hi-C etc.).
• Experience with cell culture.

We expect the candidate to be highly motivated, creative, and able to work in a multi-disciplinary team. Apart from being a true team player, we expect the candidate to exhibit a high degree of independence, have a problem-solving attitude, and have strong analytical and technical abilities in addition to excellent communication and presentation skills.

Additional Information
Benefits

The gross salary per month for our PhD will range from € 3.434 ,- to a maximum of € 4.842 ,- according to the standard PhD scales. The terms of employment will be in accordance with the Collective Labor Agreement for Hospitals. In addition you will receive a fixed end-of-year bonus (8,33%) and you will receive 8,33% holiday pay.

Your travel expenses will be reimbursed at € 0,19 per km. Free parking at the Antoni van Leeuwenhoek is also part of the package. Personnel is stimulated to use public transport and bicycle and therefore we offer an interesting arrangement for bikers and/or discount on the NS-business card.

Additional comments

Interested?

For further information and addresses, visit our website (https://www.nki.nl/research/research-groups/elzo-de-wit/ ) or contact Elzo de Wit at [email protected] .

Website for additional job details

https://www.academictransfer.com/337732/

Work Location(s)

Number of offers available

1

Company/Institute

The Netherlands Cancer Institute

Country

Netherlands

City

Amsterdam

Postal Code

1066 CX

Street

Plesmanlaan 121

Geofield

Where to apply

Website

https://www.academictransfer.com/en/337732/postdoc-vacancy-in-the-research-grou…

Contact

City

Amsterdam

Website

https://www.avl.nl/

Street

Plesmanlaan 121

Postal Code

1066 CX

STATUS: EXPIRED