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only laborious and time-consuming, but also cover only a miniscule fraction of the unimaginably large sequence space available. As a result, means to guide evolutionary trajectories along a biomolecule’s
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of putative epialleles. You will: Oversee DNA sequencing approaches for targeted analysis of DNA methylation, SNP and structural variation between accessions, including long read sequencing methods Perform
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by sequences of femtosecond laser pulses, using a suite of femtosecond time-resolved magneto-optical spectroscopies, as well as magnetic imaging using a dedicated magnetic force microscope and magnetic
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; profile root and leaf microbiomes using amplicon sequencing; analyse integrated microbiome and phenotyping datasets; contribute to machine-learning models predicting pathogen invasion success and plant
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to profile tumour and immune cells in melanoma organoid co-cultures and live tissue slices. At Erasmus MC, the candidate will work to combine spatial FUNseq with single-cell genome and transcriptome sequencing
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, physiology and disease development; profile root and leaf microbiomes using amplicon sequencing; analyse integrated microbiome and phenotyping datasets; contribute to machine-learning models predicting
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Profiling: Performing and analyzing state-of-the-art single-cell RNA sequencing (scRNA-seq) alongside bulk and single-cell epigenomic assays. o Data Integration: Collaborating with data scientists to map
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; good organisational and communication skills and an interest in working in an interdisciplinary and international environment. Experience in the complementary area, or with long-read sequencing data, is
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microbial community analysis (e.g., sequencing, bioinformatics) and/or assessing chemical stressor effects on organisms or ecosystems, along with solid skills in experimental design and data analysis. You are
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to characterize this phenomenon at single-cell resolution using whole-genome sequencing and artificial intelligence (AI)? If so, this PhD position could be an excellent fit for you! In this ZonMw-funded project