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PhD Project Title: Understanding inflammatory forms of cell death in sepsis Sepsis is a condition defined as life-threatening organ dysfunction caused by a dysregulated response to infection
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Conway Institute of Biomolecular & Biomedical Research | Dublin Bar, Leinster | Ireland | about 2 months ago
institutions world-wide. The project aims to develop three-dimensional in vitro drug discovery pathophysiology models using appropriate human cells (e.g. diabetic, fibrosis, cancer, etc.). State-of-the-art
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macrophages (an innate immune cell) contribute to kidney damage in autoimmunity (MacATAK). This is a multi-disciplinary training opportunity that includes basic biomedical research, state-of-the-art cellular
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by uncontrolled proliferation of the plasma cells. Over the last decade there have been several advances in its treatment, such as immunomodulators and proteasome inhibitors, however it remains
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www.euraxess.ie Detailed Project Description Centrosomes are the principal microtubule organising centres in animal somatic cells. They assemble the poles of the mitotic spindle, regulate cell polarity and movement
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Post Summary Cell therapy is broadly defined as the transfer of viable cells from one host to another (allogeneic) or into the same individual after storage or manipulation (autologous). One
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immune system. Neutrophils are an important immune cell required to phagocytose and kill S. aureus, however the bacterium has evolved strategies not only to evade the killing by neutrophils, but
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: expanding the target cohort for immune checkpoint inhibition. The target of immune checkpoint inhibition is the preactivated antigen-specific T cells. Our research group were among the first to report novel
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collaborative and interpersonal skills. Specific Requirements Desirable Criteria: A good understanding of nucleic acid and protein biochemistry. Prior experience with DNA assembly, mammalian cell culture
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titrations. Though collaborations they will also have the opportunity to perform cell studies. Research will be carried out in the Quinn group with access to the state of the art facilities at the School