8 Jan 2024
Job Information
- Organisation/Company
Institute of Microbiology (IMIC), Czech Academy of Sciences- Department
Laboratory of cellular and molecular immunology- Research Field
Biological sciences » Biology- Researcher Profile
First Stage Researcher (R1)- Country
Czech Republic- Application Deadline
29 Feb 2024 - 23:59 (Europe/Prague)- Type of Contract
Temporary- Job Status
Full-time- Is the job funded through the EU Research Framework Programme?
Not funded by an EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
PhD student in Laboratory of cellular and molecular immunology
Laboratory of cellular and molecular immunology seeks a highly motivated PhD student interested ina fascinating field of host-microbe interactions (subject area immunology).
About the project:
The aim of the project is to uncover the effects of diet-environment interactions between host and microbiome on nutrition and health. In addition to local processes, the effects of the composition of the animal gut microbiome on epithelial barrier function and distal organs such as the brain as well as on the development and function of the mammalian immune system will be investigated. The use of gnotobiotic experimental models allows precise control over the composition and activity of the microbiome and provides the unique opportunity to establish causal relationships between putative signaling microbial compounds. This project is part of the “Program Johannes Amos Comenius: INTERMICRO – Talking to microbes (1.1.2024 – 30.6.2028)”.
Job description:
The student will mainly perform experiments in vivo (laboratory mice) and in vitro (cell and tissue culture) aimed at deciphering the mechanisms of the mucosal immune response. The project requires active work with experimental mice - the course required by Czech law is offered in the first year of study. A small part of the project will require work with tissue and cell cultures. The applicant should have strong knowledge of the basic mechanisms of immune system functioning and immunological methods. In addition to animal models of inflammation and cancer, the project will include immunological methods (flow cytometry, ELISA, fluorescence microscopy) and molecular (micro)biology (e.g. PCR and RT-PCR, preparation of libraries for microbiota sequencing). Other tasks include data analysis, manuscript preparation and active participation in the preparation of publications and presentation of data. It is possible to start work before being accepted to the PhD program. However, the prerequisite is that the candidate passes the entrance exam and is accepted into the study program in October 2024 at the latest. This requires to submit the PhD study application before April and pass the entrance exam in June 2024.
Requirements
- Research Field
- Biological sciences » Biology
- Education Level
- Master Degree or equivalent
Skills/Qualifications
Requirements:
• MSc (or equivalent) in Immunology
• Ability to actively participate in a research program
• High levels of motivation and creativity
• Excellent communication skills and teamwork
• English, written and spoken – fluent
Specific Requirements
Candidate profile:
We are looking for motivated, hard-working and bright PhD student with strong background in immunology, holding MSc. degree in immunology, microbiology or molecular and cell biology. The scientific focus on mucosal immunology, host microbe interaction and previous experience of work with laboratory mice is a bonus. The candidate should be able and prepared to work with murine models of human diseases (inflammation and cancer) and communicate in English (spoken and written). The candidate should be a team-player and willing to work with other lab members and international collaborators.
- Languages
- ENGLISH
- Level
- Excellent
Additional Information
Benefits
What we offer:
• One year full time contract, with the possibility of extension for the entire duration of the project
• Excellent scientific background and professional growth
• Well supported project –both in terms of personnel (full-time contract) and material (budget)
• Friendly and supportive environment in a state-of-the-art facility
• A well-developed network of cooperating laboratories and institutions at home and abroad
• Two canteens available on campus
Starting date of the work: June, 2024 at the latest
Starting date of PhD program: October 2024 at the latest
Tutor: Miloslav Kverka, MD., PhD.
Workplace location: Institute of Microbiology of the Czech Academy of Sciences, Vídeňská 1083, 142 00, Prague, Czech Republic.
Selection process
Application documents:
Professional CV, letter of motivation, letter of recommendation from a mentor or project leader including their contact details.
Please send the required documents in electronic form for further processing and selection of applicants for a personal or online interview to the email address: [email protected]
Application deadline: February 29, 2024
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Institute of Microbiology (IMIC), Czech Academy of Sciences
- Country
- Czech Republic
- City
- Prague 4
- Postal Code
- 142 00
- Street
- Vídeňská 1083
Where to apply
[email protected]
Contact
- City
Prague 4- Website
https://mbucas.cz/- Street
Vídeňská 1083- Postal Code
142 00
[email protected]
STATUS: EXPIRED
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