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Field
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pathways that regulate hematopoiesis. Our current research focuses are: 1) Study of epigenetic modulation in hematopoietic stem cell differentiation using genome wide and single cell RNA seq analysis; 2
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analyze single-cell RNA sequencing (scRNA-seq) datasets using biostatistical and bioinformatics approaches. Conduct molecular, cellular, biochemical, and immunological analyses to support research
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microenvironment, and other hematological and solid neoplasms. Such models incorporate multi-omics high-throughput assays such as RNA-seq, ChIP-seq, ATAC-seq, MPRA, PC-HiC. Participates in the configuration and
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the experimental and bioinformatics analysis components—is essential. Proficiency in classical genomics techniques (RNA-seq, ChIP-seq, etc.) Proficiency in mouse ES cell culture and in vitro differentiation
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that variants have on PR-DUB and PRC1 function - using methods such as CUT&Tag, Captify, RNA-seq, immunoprecipitation followed by mass spectrometry and high throughput pooled CRISPR screens. The role
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University of California, Los Angeles | Los Angeles, California | United States | about 17 hours ago
projects in the laboratory integrate whole-genome sequencing (WGS), transcriptomics, single-cell RNA sequencing, antibody and systems-serology measurements, PhIP-Seq/epitope profiling, immunophenotyping, and
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, Skills & Abilities: Principles of bulk RNA-seq and, ideally, single-cell and/or single-nucleus RNA-seq RNA extraction, library preparation, sequencing strategies, and common sources of technical variation
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. Develop and optimize genome and epigenome editing workflows in neuronal or neural progenitor systems. Generate, analyze, and interpret multi-omic datasets (e.g., RNA-seq, ATAC-seq, ChIP/CUT&RUN/CUT&Tag
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. Main research lines Study of the “language” of chemical modifications in DNA and histones (epigenetics) and RNA (epitranscriptomics). Characterisation of multi-omic heterogeneity through single-cell
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-EM, and/or genome-wide approaches to identify novel RNA-based regulatory mechanisms using RNET-seq, Term-seq, and Structure-seq. Applicants must have recently received their Ph.D. in the Life Sciences