-
Templeton Foundation. The project seeks to discover and characterize novel RNA-based gene regulatory mechanisms in mammals, with a particular focus on riboswitches that sense lithium and sodium ions
-
characterization of mammalian riboswitches. This position, supported by a grant from the John Templeton Foundation offers an exciting opportunity to help uncover previously unknown RNA-based genetic regulatory
-
for an energetic and creative individual to help discover and characterize functional RNA elements within the human virome, the trillions of viruses that reside in the human body. This project builds on our recent
-
. Develop and optimize genome and epigenome editing workflows in neuronal or neural progenitor systems. Generate, analyze, and interpret multi-omic datasets (e.g., RNA-seq, ATAC-seq, ChIP/CUT&RUN/CUT&Tag
-
“drylab” techniques. Current drylab approaches focus on bioinformatics, including emerging artificial intelligence models. Current wetlab approaches focus on RNA and chromatin biology. Candidates should
-
-tracing mouse models, lung injury and tumor-initiation systems, single-nucleus multiome (RNA and ATAC) and spatial profiling, and validation in human early-stage lung adenocarcinoma specimens. The position
-
), ALS, long Covid and other CNS diseases. · Apply multi-omic profiling (small and long RNA-seq, lipidomics) to define exosomal cargo signatures associated with different disease states. · Develop and
-
in one or more of the following areas is especially valued: in vivo tumor or immunotherapy models, functional genomics, CRISPR, mRNA platforms, protein engineering, systems immunology, single-cell RNA
-
-cell RNA-seq) Preferred Qualifications Background in statistical or population genetics, including variant annotation and prioritization Experience with single-cell or spatial transcriptomics Familiarity
-
biosafety level 2 (BSL2+) lab), immunology (such as flow cytometry and CAR-T engineering), molecular biology (such as CRISPR, RNA biology), or animal models, (e) collaboration with other researchers both