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Field
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, Sheppard Lab and PubMLST development team, the researcher will support and analyze large bacterial genome collections to understand the epidemiology and evolution of antimicrobial resistance (AMR) in
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malignancies and to develop strategies to overcome therapeutic resistance. The Taylor laboratory uses a multidisciplinary approach that integrates molecular biology, cancer biology, genetics, genomics
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genomics, epigenomics and multi-omics approaches to investigate mechanisms of tumour development, treatment response and resistance, with a clear focus on preclinical validation and clinical translation
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molecular mechanisms of cancer progression, metabolic reprogramming, therapeutic resistance, and tumor–immune interactions. The Postdoctoral Associate will work with diverse datasets that includes bulk RNA
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and characterise genetic sources of crown rust resistance in oat germplasm generate high-quality greenhouse and field phenotypic and genotypic datasets to support identification of resistance loci
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glioblastoma models, cerebral organoids and single-cell epigenomics to understand how epigenetic heterogeneity drives treatment resistance and recurrence. The post holder will lead the experimental programme
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Description: The successful applicant must be a Molecular Entomologist who will be part of the insecticide resistance group and he/she will mainly work on resistance mechanisms and contributing to the overall
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vulnerabilities in drug resistant, KRAS- and EGFR-mutant NSCLC and inform the development of ferroptosis-targeted treatments to improve treatment outcomes and survival for patients with lung cancer. Location
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that will improve our understanding of therapeutic response and resistance in colorectal cancer. Colorectal Cancer- Stratification of Therapies through Adaptive Responses (CRC-STARS) is a CRUK strategic
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Position Summary Perform various cell and molecular biology experiments to study the fundamental mechanism of gene transcription, RNA biology, and their relation to cancer development and drug resistance