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organic synthesis, with preferred additional experience in protein purification and in vitro binding assays. The project addresses a critical need for the discovery and validation of novel therapeutic
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Lab investigates the structure, dynamics, and regulatory mechanisms of RNA and RNA-protein complexes that maintain genome integrity, mediate innate immunity, and impact human health. Using a combination
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multi-photon), viral vectors, protein engineering, mouse models, and multi-omics analyses. For further information on the lab, please visit: www.shigroup.org We welcome applications from postdoctoral
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molecular and cellular biology concepts, such as protein interactions, molecular assemblies, gene regulation, cellular organization, or biological networks. Candidates must be independent self-starters, have
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opportunities for eventual clinical translation. An area of advanced research and interest in the lab is investigating proteins critical for DNA damage repair in bone tumors, alternative lengthening of telomeres
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themes is uncovering how the structural colors seen in bird feathers arise through the phase separation and self-assembly of proteins. Depending on their own expertise and interests, successful applicants
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goals. Our research focuses on neurovascular signaling, utilizing mouse genetics, molecular and protein-biochemical methods, cell biology, and various -omics methods. Currently, we are exploring
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systems (proteins, enzymes, membranes, and complexes) Integrate AI/ML approaches with physics-based simulations to accelerate discovery and improve predictive fidelity Contribute to cross-scale modeling
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targets specifically amyloidogenic proteins implicated in the diseases like Alzheimer’s and Parkinson’s. Required qualifications A PhD. In the area of synthetic/ medicinal chemistry is rquired. Experience
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molecules from various biological matrices. Knowledge of various extraction protocols (protein precipitation, liquid-liquid extraction, solid phase extraction, etc.). Hands-on experience with different