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Summary A postdoctoral fellow position is available in the laboratory of Anna Moszczynska, Ph.D., to study cellular and molecular mechanisms underlying the anti-addictive properties of protein
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for protein-protein interactions), Chromatin immunoprecipitation (ChIP) and ChIP-sequencing sample prep, Cloning and plasmid construction (e.g., CRISPR/Cas9 vector design for gene editing), and Lentiviral
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targets specifically amyloidogenic proteins implicated in the diseases like Alzheimer’s and Parkinson’s. Required qualifications A PhD. In the area of synthetic/ medicinal chemistry is rquired. Experience
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of interaction partners of specific small G proteins (e.g., Rac1) and its corresponding signaling pathways in islet beta cells exposed to metabolic stress. Evaluate novel small molecule inhibitors of Rac1 in
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Summary The fellow will be involved in studies, which are aimed at understanding G protein-mediated signaling mechanisms underlying islet beta-cell function in health and diabetes. Specifically
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. This position will involve laboratory work in drug discovery, biocatalysis, protein engineering, synthetic biology, molecular biology, and natural product biosynthesis, which is ideally suited for individuals who