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post, starting January 2027 within the lab of Prof. Clare Davies (https://www.claredavieslab.org/) and Dr. Susanne Gatz at the Department of Cancer and Genomic Sciences, investigating oncogenic
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of proteolytic systems and the deployment of innate immune strategies that enable survival during phage attack. In addition, another major focus of our research is protein engineering and the development of new
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or without notice. Required Qualifications Work Experience: 4 years experience in protein biochemistry, including the expression and purification of recombinant proteins and the functional analysis of proteins
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, which may include nucleic acid extraction, cloning, PCR, RT-qPCR/qPCR, sequence analysis, Agrobacterium-mediated infiltration, library preparation, gene-expression analysis, and protein–protein
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, live-cell and high-content imaging, and analysis pipelines such as ImageJ/Fiji, Imaris, or QuPath – Experience investigating small-molecule mechanisms of action, protein-protein interaction dynamics, and
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, and Jeffrey H. Chuang. 2012. “Transcriptional Enhancers in Protein-Coding Exons of Vertebrate Developmental Genes.” PloS One 7 (5): e35202. https://doi.org/10.1371/journal.pone.0035202 . Although cis
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, and in vitro disease modeling Strong publication record demonstrating independent research capability Extensive experience with molecular and protein analysis techniques (qPCR, Western blot
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-on experience with metabolomics samples preparation and measurement by LC/MS or GC/MS. A demonstrated proficiency in protein chemistry and protein biophysical analysis are also preferred. Prior experience with
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), assessing protein quality for subsequent characterization and structural analysis; performing biochemical and biophysical assays to assess sample stability, folding and oligomerization state, as
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motifs; - establish, optimize, and apply quantitative protein-interaction assays; - perform mammalian cell culture, molecular cloning, mutational analysis, recombinant protein work, and fluorescence