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related to biomedical sciences, with preference for experience in physiology or cardiovascular sciences; Experience with (endothelial or cardiac) cell culture, protein biochemistry, in vitro models using
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with: A master’s degree in a field related to biomedical sciences, with preference for experience in physiology or cardiovascular sciences; Experience with (endothelial or cardiac) cell culture, protein
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, in parallel, explore CRISPR and AAV technologies to develop new ocular gene therapy. We have all multidisciplinary facilities, technology and expertise needed directly at our disposal. The candidate
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on the cytokine responses of macrophages; Next to cell culture experiments, you will use and analyze state-of-the-art approaches such as RNA-sequencing and ChIP-sequencing analysis; Translate your findings
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of Twente and Wageningen, to detect RNA biomarkers with CRISPR-Cas13. This technology is ultra-sensative and may revolutionize ‘point of care ‘cancer diagnostics. You will work with state-of-the-art
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treatment technology for applying and monitoring effective novel personalized breast cancer treatments combining MR-guided local thermotherapy with ‘smart’ nano-chemotherapy. This project is supported by a
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sciences or biology; Experience with iPSC models and/or extensive cell culture experience with other cell types; Hands-on experience with CRISPR or assay development is an advantage, but not required
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matter-like environment. With the use of various co-culture systems, sophisticated microscopy, RNA sequencing, and functional assays, you will aim to assess the differential role human microglial cells
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of macrophages; Next to cell culture experiments, you will use and analyze state-of-the-art approaches such as RNA-sequencing and ChIP-sequencing analysis; Translate your findings to disease models; Align
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to different receptors; Study the capacity of nanobodies to block infection by pathogens and develop and test nanobody based vaccines using human in vitro culture systems; Work closely with our collaborators