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to modern medicine, and bacteriophage therapy is a promising route to treat drug-resistant infections. Yet phage therapy can fail when bacteria evolve resistance or deploy defence systems that block
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The GW4 BioMed3 Doctoral Landscape Programme is offering up to 18 MRC funded studentships across a As antibiotic resistance threatens modern medicine, phage therapy is emerging as a powerful new
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to modern medicine, and bacteriophage therapy is a promising route to treat drug-resistant infections. Yet phage therapy can fail when bacteria evolve resistance or deploy defence systems that block
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physiological state shapes bacteriophage infection. We aim to determine how dormancy, nutrient limitation, growth transitions and stress generate transient phage resistance or tolerance, identify the underlying
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The project The bacterial Type 6 secretion system (T6SS) is one of the largest dynamic assemblies in Gram-negative bacteria. It shares evolutionary origins with contractile phage tails and other
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bacterial physiological state shapes phage infection dynamics and how this knowledge can be used to design more effective phage-based antimicrobial interventions. The successful applicant will work with a