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plasticity between quiescent and proliferative stages, where immunoregulatory functions are acquired, 2) the tolerogenic and metabolic mechanisms underlying the retention of a proliferative pool of leukemic
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the central role of immunity in the cancer fight. Although revolutionary, this therapeutic approach does not yet provide the expected results for all patients. In this context, the team TICI (Therapuetic
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). The functional optimization of T lymphocytes used for these immunotherapy strategies is now at the forefront of our current preoccupations. In this context, recent advances in T cell biology, molecular modulation
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on the use of synthetic (bio)materials, but very often only on autologous tissues, which has a significant impact on the patient. Thus, in recent years, the Unit has developed materials 100% based on albumin
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macrophages toward a pro-inflammatory, anti-leukemic state. The work will combine human monocyte-derived macrophage models, leukemia-conditioned macrophages, primary AML patient samples, chemical biology
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researcher for a 3-year position to work on a project aimed at identifying new therapeutic strategies targeting the NF-κB pathway in two hematological malignancies: multiple myeloma and mantle cell lymphoma
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-year research assistant position to work on the “Math-O-Meter” project, led by Marie Amalric. Project description The project aims to follow the integration of new mathematical concepts across the school
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investigating the mechanisms underlying cardiac and vascular diseases. It extends ongoing work developed over several years on heart failure with preserved ejection fraction (HFpEF), as well as research conducted
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decision making are intertwined processes in many everyday situations. One example is when you decide where to have lunch: should you go to the nearby coffee shop or to the university cafeteria? Learning
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and to contribute to the diversification and enrichment of our scientific programs. He/she will also play a key role in teaching and mentoring students. The candidate will benefit from strong