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this will be addressed using advanced NMR methods. and integrative modelling, providing real- insights into conformational changes governing CB1R selectivity. This project offers the opportunity
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equipped with everything necessary for the successful completion of the proposed research. Some equipment has been recently renewed: 600 MHz NMR (2026), HRMS (2026), chiral HPLC (2026); other equipment will
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laboratories: the Institut de Chimie Moléculaire-ICMG for NMR spectroscopy, mass spectrometry (MS), X-ray diffraction, and EPR. The development of artificial photosynthesis systems for water splitting and CO
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, GC-MS/MS, and advanced NMR approaches. - **Activity 4:** Multivariate statistics and machine learning to identify microbial and chemical biomarkers of resilience and reveal the interactions linking
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programming tools (Matlab, Python, C++) is essential, and knowledge of NMR/MRI would be a valuable asset. Mechanistic insights and optimization of synchronized respiratory stimulation as a therapeutic
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of nanoparticle formation through Small Angle X-ray Scattering (SAXS) and Raman spectroscopy. Automated sampling during polymerisation will enable complementary ex situ analyses including SEC, NMR and HPLC
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focuses on the structural and dynamic characterization of intrinsically disordered and multidomain proteins involved in major biological processes, combining experimental biophysics approaches (SAXS, NMR
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using isotopic exchange and solid-state NMR, and the investigation of the influence of microbial activity on the evolution of these properties. The PhD work will involve: Setting up controlled incubations
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. The creation of magnets producing 20 T or more is a major challenge for physics (NMR, high-energy physics) as well as for the realization of compact Tokamaks, which have become highly attractive in recent years