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Field
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basis of fungal virulence including through genetic manipulation and next-generation sequencing approaches; Testing of novel antifungal compounds on fungal critical threat pathogens; Developing novel
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. Preferred Experience with antisense oligonucleotides, RNA therapeutics, alternative splicing, or RNA biology. Experience working with mouse models of disease. Experience with next-generation sequencing and
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–DNA interactions, the genetic and epigenetic features of DNA sequences, and the three-dimensional (3D) organization of the genome and its regulatory landscape. A particular focus will be on integrating
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sequences, achieving rapid detection at femtomolar concentrations whilst maintaining robust separation between true-positive and negative reactions. The post-holder will work closely with research fellow will
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science and the practice of medicine. Across British Columbia, more than 12,000 faculty and staff are training the next generation of doctors and health care professionals, making remarkable discoveries
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method development, data analysis, and experimental design. Integrate information from high-throughput screens, proteomic data, and next-generation sequencing data to generate and validate hypotheses
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molecular microbiology focus / develop next-generation diagnostics for infectious diseases / collaborate with clinical and industry partners. Join the Huston Lab to advance infectious disease diagnostics and
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diverse sources of biological information, including the biophysical principles governing protein–DNA interactions, the genetic and epigenetic features of DNA sequences, and the three-dimensional (3D
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–DNA interactions, the genetic and epigenetic features of DNA sequences, and the three-dimensional (3D) organization of the genome and its regulatory landscape. A particular focus will be on integrating
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state-of-the-art methods generative protein design, directed evolution, next gen sequencing, and laboratory automation to develop B12-dependent enzymes or artificial metalloenzymes containing different