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observables in both systems. Anderson, P.W. 1972. More is di1erent. Science 177:393-396. Eberl, G. 2026. An elementary model of homeostasis and immunity that generates symbiosis. bioRxiv https://doi.org
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on the specific questions addressed, approaches may include mammalian cell culture, molecular and cell biology, genetic perturbation, imaging, epigenetic and chromatin profiling, and in vivo models of early
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secondments (lab exchanges). The doctoral candidate will utilize cutting-edge techniques: Cell and tissue culture (human primary and stem cell-derived retinal models) Molecular biology and biochemistry
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sample, and in vivo leukemia models Perform and oversee molecular, cellular, genomic, and functional assays Analyze, interpret, and integrate multi-omics datasets to generate biologically meaningful
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cells. Compounds identified through a pharmacological screening approach represent promising therapeutic leads, including in models of bortezomib-resistant cell lines. The project combines a fundamental
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interpretable models that connect molecular patterns across multiple scales of human biology. The project lies at the interface of artificial intelligence, computational biology, systems medicine, and precision
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production provides a competitive advantage to commensal bacteria, thereby limiting the establishment of pathogenic strains. This work adopts a multidisciplinary approach, combining methods from molecular
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activity in vitro; basic knowledge of bioinformatics, molecular modelling and docking and/or structural analysis of protein–ligand complexes, as well as the ability to use in silico results to guide
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postdoctoral position is available in the laboratory of Prof. Alex Persat (EPFL School of Life Sciences, https://www.p-lab.science/ ) to establish a new image-based drug screening platform targeting gram
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of Duties Explore molecular mechanisms linking to cancer, obesity, liver, women diseases using a combination of biochemical and molecular techniques in cultured cells, xenografts, and engineered mouse models