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, from understanding disease mechanisms and developing disease models to preclinical therapy testing, clinical readiness and patient-informed treatment priorities. To achieve this, POLARIS brings together
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mechanisms and developing disease models to preclinical therapy testing, clinical readiness and patient-informed treatment priorities. To achieve this, POLARIS brings together expertise in leukodystrophy
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of coronary artery disease and supporting clinical decision-making during catheterization procedures. The project brings together cardiovascular imaging, generative AI, and computational modeling to develop
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mechanisms and model development to preclinical therapy testing, clinical readiness and patient-informed treatment priorities. To achieve this, POLARIS brings together expertise in leukodystrophy biology
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two clinical studies in Kenya and Zambia, assessing whether E. coli carriage contributes to Enterobacteriaceae colonization and ARG transmission. Finally, the PhD student will use agent-based modeling