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The Faculty of Science and Engineering (FSE) provides teaching and research across a wide range of disciplines, from physics and biology to artificial intelligence, mechanical engineering, and pharmacy. In close collaboration with partners from industry, healthcare, and society, we contribute to...
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at the interface of biophysical modeling, soft matter and cell mechanobiology at the Groningen Research Institute of Pharmacy, within the Faculty of Science and Engineering at the University of Groningen. What
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heterogeneity. Subsequently, the technology will be adapted and translated to the characterization of particles in environmental samples. The project combines flow cytometry, multidimensional data analysis, cell
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organoids and immune-competent gut–microbe co-culture models to examine how early microbial colonisation affects immune-cell development, gut epithelium and immunity, with particular attention to naïve T-cell
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Fatigue profoundly impacts mobility and quality of life in people with neurological disorders, yet its effects on everyday movement remain poorly understood. In this PhD project, you will combine
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-) immunoprecipitations from neuronal cell models and brain tissue followed by quantitative LC-MS/MS, and you will run that workflow from end to end – from sample preparation to data analysis and interpretation. Candidate
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epigenetic editing delivered via lipid nanoparticles; Using a combination of cell models and human donor livers, you will investigate how these technologies can improve organ quality and increase the number
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/or scNMT-seq workflow for multimodal profiling of melanoma models and tissue samples. The project will translate the protocol developed by DC3 into 3D melanoma organoid and immune cell co-cultures
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, immunology or a closely related field; - experience with relevant laboratory techniques such as mammalian cell culture, molecular biology, immunological assays, flow cytometry and/or virological methods
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a potential drug target in a subgroup of people with MLC by researchers in Pediatric Neurology at Amsterdam UMC. GPCRs are cell-surface proteins that respond to external stimuli and are widely