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at Faculty of Medicine and MultiPark at Lund University. Our research aims to uncover how microglia dynamically modulate neural circuits to shape memory formation and extinction across health, psychiatric
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The Mancuso lab studies microglia — the resident immune cells of the brain — and their role in neurodegenerative disease. We generate microglia from human induced pluripotent stem cells (iPSCs
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The Mancuso lab studies microglia — the resident immune cells of the brain — and their role in neurodegenerative disease. We generate microglia from human induced pluripotent stem cells (iPSCs
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The Gliomics Research Group (https://www.gliomics-lab.com/) is located at the Center for Neuroscience at UC Davis. Our group is interested in understanding the genetic regulation of microglia states
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contribution of TNTs and EVs to astrocyte—neuron and microglia—neuron communication during tau pathology propagation. The study will examine how tau-induced cellular stress modulates TNT formation
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, astrocytes, oligodendrocytes, and microglia. Develop complex neuroimmune co-culture systems incorporating immune cells into human CNS models. Apply CRISPR/Cas-based genome engineering technologies
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cells -Cultures of human iPSC-derived microglia -Functional assays: cytokine expression measurements, ROS release, mitochondrial viability -Immunofluorescence, including quantitative approaches
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neurodegeneration, microglial activation, microglia-vascular interactions and angiogenesis, tissue injury and repair, and therapeutic response. The position will integrate in vivo ocular disease models, primary
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proteomics, single-cell genomics, CRISPR genome engineering, and human iPSC-derived microglia and motor neuron models, our goal is to identify novel therapeutic targets that can be translated into effective
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mouse models relevant to MS pathogenesis and recovery. Performing and overseeing cellular and molecular studies involving macrophages, microglia, and other CNS-resident or infiltrating immune cells