Research Technician - Hahn Lab

Posted: 01-Mar-24

Location: Boston, Massachusetts

Salary: Open

Internal Number: 2024-38467

We are seeking a highly motivated Research Technician to join the Hahn lab's scientific research team studying mechanisms of cancer initiation and progression as well as novel therapeutic targets. This role contributes to current laboratory-based projects using functional genomics, organoids and single cell approaches to understand oncogene cooperation and combination therapies.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong.?? As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff.?? Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

The candidate will work with a mentor to assist in the generation and cultivation of 3D models from primary human tumors and cell lines and help in the characterization of cell surface marker expression using a variety of immunological assays combined with biochemical and molecular biology techniques. They will perform extensive cell and tissue culture, basic molecular biology techniques relating to DNA/RNA and protein work (cloning, Western blotting, immunoprecipitation, protein purification, etc???). In addition, the successful candidate will perform modern functional perturbation techniques including lentiviral knockdown and genome editing tools to validate candidate targets.

The candidate will additionally assist with overall lab management including inventory maintenance, reagent tracking, common stock reagent preparation and other related organizational tasks as needed.

• Set up, adjust, calibrate, clean, maintain and troubleshoot equipment.
• Clean, maintain and prepare supplies and work areas and may be responsible for ordering of supplies. Collaborates with Purchasing and may be responsible for negotiating with vendors.
• Analyze experimental data and interpret results to write reports and summaries of findings, including grant preparation and presentations, and look for opportunities to co-author publications. May be expected to participate in formal and information presentations of results to staff.??
• Participate in grant application process and manuscript preparation as required.
• Maintains detailed notebook of all work-related activities.
• Monitors laboratory work to ensure compliance with Environmental Health and Safety information as well as the standard operation procedures specific to each laboratory.
• Expected to provide intellectual and interactive commitment to position by keeping up with appropriate literature and research publications.
• May be responsible for the development, modification and improvement of standard operating procedures.
• Uses computers, computer-interfaced equipment, robotics or high-technology applications to perform work duties.
• May be responsible for designing and executing advanced experiments and setting strategy.??
• May be responsible for the examination of animals and specimens to detect the presence of disease or other problems.
• May be responsible for monitoring laboratory budgets.

The ideal candidate will be scientifically curious, self-motivated, detail and goal-oriented and possess excellent organizational skills including the ability to handle a variety of tasks in a fast-paced environment as well as strong interpersonal, communication, and analytical skills. A positive attitude and ???team-player??? mindset is essential. A two-year commitment is required.

• Bachelor's Degree required with a major in Biological or Biochemical Sciences preferred.??
• Familiarity of basic cell culture, molecular biology laboratory and/or immunological techniques is strongly desired.
• Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
• Ability to analyze information and use logic to address work-related issues and problems.
• Must have attention to detail and be thorough in completing work tasks.
• Ability to work within a team environment.

KNOWLEDGE, SKILLS AND ABILITIES REQUIRED:

• Knowledge of information and techniques related to either biology, chemistry, or medicine is preferred.
• Must have excellent communication skills (written and verbal) and be able to work with a wide variety of faculty and staff.
• Ability to analyze information and use logic to address work-related issues and problems.
• Must have attention to detail and be thorough in completing work tasks.
• Ability to work within a team environment.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law.

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About Dana-Farber Cancer Institute
Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to under-served members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
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