Research Scientist

University of Pittsburgh, United States

Updated: about 2 months ago

Research Scientist
Med-Medicine - Pennsylvania-Pittsburgh - (26004131)
 

Overall Lab Summary

Our research group operates at the intersection of computational biology, systems medicine, and translational science within the Vascular Medicine Institute (VMI). We focus on integrating large-scale omics data with mechanistic modeling to uncover systemic drivers of disease. This project provides a unique opportunity to work on NASA spaceflight data while developing broadly applicable frameworks for understanding organ dysfunction and therapeutic intervention.

 Job Duties

    • Integrate and analyze multi-modal transcriptomic datasets (bulk RNA-seq, single-cell RNA-seq, spatial transcriptomics, and time-series data). 

    • Identify disease molecular signatures under spaceflight and simulated conditions. 

    • Construct and analyze gene regulatory networks (GRNs) to infer upstream regulators. 

    • Develop and apply deep learning–based drug repurposing approaches to identify compounds that reverse space flight-induced regulatory disruptions. 



Job Summary

Conducts independent scientific research projects from inception to presentation. Prepares and crafts various documentations of research results into manuscripts, proposals, grant applications, and presentations. Trains undergraduates and research technicians. Manages laboratory policies and coordinates project development in collaboration with other specialists.


Essential Functions 

  • PhD-level knowledge in computational biology, bioinformatics, systems biology, data science, or a related field. 

    • Strong experience in transcriptomic data analysis, experience with spatial transcriptomics is a plus. 

    • Demonstrated expertise in statistical learning or machine learning. 

    • Experience with network biology, pathway analysis, or gene regulatory network inference. 

    • Ability to work independently on complex, interdisciplinary projects.


Physical Effort 

Position is hybrid.  Must be able to move between VMI offices and labs as needed.  Most sedentary.

 


The University of Pittsburgh is an equal opportunity employer / disability / veteran.

 
Assignment Category Full-time regular
Job Classification Staff.Research Scientist
Job Family Research
Job Sub-Family Research Science
Campus Pittsburgh
Minimum Education Level Required Professional Doctorate Degree
Minimum Years of Experience Required 5
Will this position accept substitution in lieu of education or experience?  No
Work Schedule mon-friday standard
Work Arrangement Hybrid: Combination of On-Campus and Remote work as determined by the department.
Hiring Range To be determined based on qualifications
Relocation Offered No
Visa Sponsorship Provided No
Background Check For position finalists, employment with the University will require successful completion of a background check
Child Protection Clearances Not Applicable
Required Documents Resume
Optional Documents Not Applicable

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